Friday, February 27, 2015
FAIRFIELD-SUISUN, CALIFORNIA
99 CENTS

Progress made on a ‘bionic pancreas’ for diabetics

Diabetes Bionic Pancreas

This undated product image provided Boston University Department of Biomedical Engineering shows the bionic pancreas developed by a Boston University/Massachusetts General Hospital research team. The bionic pancreas consists of a smartphone, top, hardwired to a continuous glucose monitor and two pumps, bottom, that pumps deliver doses of insulin or glucagon every five minutes. (AP Photo/ Boston University Department of Biomedical Engineering)

By
From page A5 | June 16, 2014 |

BOSTON — Scientists have made big progress on a “bionic pancreas” to free some people with diabetes from the daily ordeal of managing their disease. A wearable, experimental device passed a real-world test, constantly monitoring blood sugar and automatically giving insulin or a sugar-boosting drug as needed, doctors said Sunday.

The device improved blood-sugar control more than standard monitors and insulin pumps did when tested for five days on 20 adults and 32 teens. Unlike other artificial pancreases in development that just correct high blood sugar, this one also can fix too-low sugar, mimicking what a natural pancreas does.

The device was developed at Massachusetts General Hospital and Boston University. Results were featured Sunday at an American Diabetes Association conference in San Francisco and were published online by the New England Journal of Medicine.

“I’m very excited about it,” said Dr. Betul Hatipoglu, an endocrinologist at Cleveland Clinic who had no role in the work. Many patients have been frustrated waiting for a cure, so “this is really a great new horizon for them,” she said.

The bionic pancreas is for Type 1 diabetes, the kind often found during childhood. About 5 percent of the 26 million Americans with diabetes have this type and cannot make insulin to turn food into energy. Sugar builds up in the blood, raising the risk for heart disease and many other problems.

These people must check their blood and inject insulin several times a day or get it through a pocket-sized pump with a tube that goes under the skin.

“This would lift that burden off of their shoulders,” Dr. Steven Russell, a diabetes specialist at Massachusetts General, said of the bionic pancreas he helped design.

It has three parts: two cellphone-sized pumps for insulin and sugar-raising glucagon, and an iPhone wired to a continuous glucose monitor. Three small needles go under the skin, usually in the belly, to connect patients to the components, which can be kept in a fanny pack or a pocket.

Patients still have to prick their fingers to test blood sugar twice a day and make sure the monitor is accurate, but the system takes care of giving insulin or glucagon as needed.

Kristina Herndon said her 13-year-old son, Christopher, “loved it” when he tried it for the study, and “felt pretty badly giving it back” when it ended. Christopher has to check his blood sugar eight to 10 times a day and his family has to watch him closely in case it dips too low while he sleeps, which can cause seizures or even death.

“It’s a disease that I think people think is not a big deal but it’s tough. It’s hard on a family,” said Herndon, who lives in Newburyport, Massachusetts.

Next steps: A study starts Monday in 40 adults who will use the device for 11 days. By fall, researchers hope to have a next-generation version combining all three components in one device to be tested in studies next year aimed at winning federal Food and Drug Administration approval.

“My goal is to have this device done by the time my kid, who has Type 1 diabetes, goes to college” in about three years, said Ed Damiano, a biomedical engineer at Boston University.

Two San Diego-based companies – DexCom and Tandem Diabetes Care Inc. – made components of the version tested in the current study. Boston University and Massachusetts General own or have patents pending on the system, and several researchers may someday get royalties.

Medtronic, Johnson & Johnson and several other companies also are working on artificial pancreas devices.

The Boston group’s work is exciting and the results are compelling, but there still are practical challenges to bringing a device to market, said Aaron Kowalski, who oversees grants by the Juvenile Diabetes Research Foundation on artificial pancreas development.

“Most people with diabetes want less devices in their lives, not more,” so putting the components into a single automated system is key, he said.

The Associated Press

The Associated Press

LEAVE A COMMENT

Discussion | 1 comment

The Daily Republic does not necessarily condone the comments here, nor does it review every post. Read our full policy

  • JimboJune 16, 2014 - 4:00 pm

    B-b-but the Alex Jones lovers will be afraid Al Quada will be hacking the device in their quest for world domination.

    Reply | Report abusive comment
.

Solano News

Police investigate Fairfield’s 2nd homicide of 2015

By Glen Faison | From Page: A1, 1 Comment | Gallery

 
Lawyer: Defendant to testify in police shooting case

By Jess Sullivan | From Page: A1

Fairfield mayor ready to share a whale of a tale

By Amy Maginnis-Honey | From Page: B1

 
Oakland author, vet talks about researching Vietnamese side of war

By Ian Thompson | From Page: A1 | Gallery

Nonagenarian recounts life as spy in World War II

By Amy Maginnis-Honey | From Page: B1

 
 
Republican women to hear about immigration reform

By Amy Maginnis-Honey | From Page: A3

 
2-day event will focus on bullying prevention

By Amy Maginnis-Honey | From Page: A3

 
Kaiser offers Capoot scholarships

By Bill Hicks | From Page: A4

 
Copter makes emergency landing in Vacaville

By Ryan McCarthy | From Page: A4

Wolk to chair committee on state’s wine industry

By Kevin W. Green | From Page: A4

 
SafeQuest Solano plans garage sale, seeks donations

By Susan Hiland | From Page: A4

Suisun City police log: Feb. 25, 2015

By Susan Hiland | From Page: A12

 
Fairfield police log: Feb. 25, 2015

By Susan Hiland | From Page: A12

.

US / World

Llamas on the loose trends on Twitter

By The Associated Press | From Page: A2

 
Two inured in hazmat explosion

By The Associated Press | From Page: A4

No charges yet for train crash truck driver

By The Associated Press | From Page: A4

 
Missing 400-year-old Italian books found in California

By The Associated Press | From Page: A5

Sacramento man pressured to remove swastikas

By The Associated Press | From Page: A5

 
Not guilty plea for suspect in Hollywood exec murder

By The Associated Press | From Page: A5

 
After 67 years of marriage, couple dies holding hands

By The Associated Press | From Page: A5

Feds: 3 accused in Islamic State plot vocal about beliefs

By The Associated Press | From Page: A6

 
Saudi man convicted of conspiracy in ’98 US embassy bombings

By The Associated Press | From Page: A7

If Supreme Court says no, they’d lose health insurance help

By The Associated Press | From Page: A7

 
Panel: Use new meningitis vaccines only for outbreaks

By The Associated Press | From Page: A7

VA chief backs outside medical care as new program falters

By The Associated Press | From Page: A7

 
House GOP weighs new approach on Homeland Security

By The Associated Press | From Page: A7

Vandalism in Arizona shows the Internet’s vulnerability

By The Associated Press | From Page: A7

 
Prosecutor: Mom craved attention, poisoned child with salt

By The Associated Press | From Page: A7

Ukraine, rebels start pulling back heavy weapons in the east

By The Associated Press | From Page: A10

 
‘Jihadi John’ raised in UK, studied computers, reports say

By The Associated Press | From Page: A10

Militants abduct more Christians, smash ancient artifacts

By The Associated Press | From Page: A10

 
.

Opinion

 
Greece v. Europe: Too soon to say who won

By Clive Crook | From Page: A11

 
Who’s in charge?

By Bud Stevenson | From Page: A11

.

Living

Today in History: Feb. 27, 2015

By The Associated Press | From Page: A2

 
Community Calendar: Feb. 27, 2015

By Susan Hiland | From Page: A2

Horoscopes: Feb. 27, 2015

By Holiday Mathis | From Page: A9

 
I’m worrie about how my wife’s erratic behavior is affecting our kids

By Kathy Mitchell and Marcy Sugar | From Page: A9

.

Entertainment

Week in preview Feb. 27-March 5, 2015

By Amy Maginnis-Honey | From Page: B1

 
Conan O’Brien takes his show to Cuba for a special hour

By The Associated Press | From Page: B2

Review: Smith, Robbie pour on the charm in sharp ‘Focus’

By The Associated Press | From Page: B2

 
Custom dress Lupita Nyong’o wore at Oscars reported stolen

By The Associated Press | From Page: B2

ABC’s Sawyer does prime-time prison special

By The Associated Press | From Page: B3

 
Q&A: Writer-director-actor Mark Duplass is a busy guy

By The Associated Press | From Page: B3

Actor Will Patton charged with DUI in native South Carolina

By The Associated Press | From Page: B3

 
AP Exclusive: Redmayne lends voice to “Thomas & Friends”

By The Associated Press | From Page: B3

Entertainment Calendar: Feb. 27, 2015

By Susan Hiland | From Page: B4

 
Tea Leoni in a happy state as star of ‘Madam Secretary’

By The Associated Press | From Page: B5

Graceland brings Elvis back to his Las Vegas home

By The Associated Press | From Page: B6

 
TVGrid

By Daily Republic Syndicated Content | From Page: B6

.

Sports

 
A’s begin baseball’s mandatory domestic violence training

By The Associated Press | From Page: B7

 
Earthquakes set to open new MLS stadium

By The Associated Press | From Page: B7

LeBron scores 42, Cavs beat Warriors for 18th win in last 20

By The Associated Press | From Page: B7

 
Bulls say Rose to have surgery on Friday

By The Associated Press | From Page: B8

NASCAR back on track for extra day of testing in Atlanta

By The Associated Press | From Page: B8

 
No word on possible MLB discipline for Angels star Hamilton

By The Associated Press | From Page: B8

Giants closer Casilla hit on shin during batting practice

By The Associated Press | From Page: B8

 
LeBron not happy colleges recruiting 10-year-old son

By The Associated Press | From Page: B8

IOC member, once critical of Rio, now sees ‘great progress’

By The Associated Press | From Page: B8

 
Judge rules for Peterson, opening door for reinstatement

By The Associated Press | From Page: B8

Herman survives windy day; McIlroy stumbles at Honda Classic

By The Associated Press | From Page: B8

 
Roberts, NBA writers open discussion over locker room access

By The Associated Press | From Page: B8

IOC relaxes rule on athletes and sponsors during Olympics

By The Associated Press | From Page: B8

 
Nevada gambling regulators sign off on Olympic betting

By The Associated Press | From Page: B8

Video shows Hernandez dancing near gas pump before killing

By The Associated Press | From Page: B8

 
Kings’ Collison to have surgery, re-evaluated in 3-6 weeks

By The Associated Press | From Page: B8

AP source: 49ers to bid to host college football title game

By The Associated Press | From Page: B8

 
.

Business

Volkswagen Jetta is a pleasure to live with, not just to gawk at

By Washington Post | From Page: C1 | Gallery

 
5 things to know about ‘net neutrality’

By The Associated Press | From Page: A1

Regulators approve tougher rules for Internet providers

By The Associated Press | From Page: A1

 
Strong reliability scores should help Buick brand’s rebirth

By The Associated Press | From Page: C2

Nissan executive known as ‘father of the Z’ dies at 105

By The Associated Press | From Page: C2

 
Medical marijuana passes tough first hurdle in Utah

By The Associated Press | From Page: B11

Applications for US jobless aid rise to 313,000

By The Associated Press | From Page: B11

 
Google looks for more revenue from ads in Android app store

By The Associated Press | From Page: B11

Walmart CEO wading through mounting issues

By The Associated Press | From Page: B11

 
Pew study: Americans still stressed despite improved economy

By The Associated Press | From Page: B11

Facebook allows users to ‘fill in’ gender option

By The Associated Press | From Page: B11

 
.

Obituaries

Donald Grimm

By Nancy Green | From Page: A4

 
Gabriel T. Traub

By Nancy Green | From Page: A4

Maria Kraszewski

By Nancy Green | From Page: A4

 
.

Comics

Frank and Ernest

By Daily Republic Syndicated Content | From Page: A8

 
Baby Blues

By Daily Republic Syndicated Content | From Page: A8

B.C.

By Daily Republic Syndicated Content | From Page: A8

 
Get Fuzzy

By Daily Republic Syndicated Content | From Page: A8

Rose is Rose

By Daily Republic Syndicated Content | From Page: A8

 
Wizard of Id

By Daily Republic Syndicated Content | From Page: A8

Zits

By Daily Republic Syndicated Content | From Page: A8

 
Blondie

By Daily Republic Syndicated Content | From Page: A8

Baldo

By Daily Republic Syndicated Content | From Page: A8

 
For Better or Worse

By Daily Republic Syndicated Content | From Page: A8

Sally Forth

By Daily Republic Syndicated Content | From Page: A8

 
Dilbert

By Daily Republic Syndicated Content | From Page: A8

Peanuts

By Daily Republic Syndicated Content | From Page: A8

 
Beetle Bailey

By Daily Republic Syndicated Content | From Page: A8

Pickles

By Daily Republic Syndicated Content | From Page: A8

 
Garfield

By Daily Republic Syndicated Content | From Page: A8

Cryptoquote

By Daily Republic Syndicated Content | From Page: A9

 
Bridge

By Daily Republic Syndicated Content | From Page: A9

Word Sleuth

By Daily Republic Syndicated Content | From Page: A9

 
Sudoku

By Daily Republic Syndicated Content | From Page: A9

Crossword

By Daily Republic Syndicated Content | From Page: A9