Monday, December 22, 2014
FAIRFIELD-SUISUN, CALIFORNIA
99 CENTS

Ancient gene aids Tibetans with high altitude

By
From page A5 | July 03, 2014 |

NEW YORK — Tibetans living on the “roof of the world” can thank an extinct human relative for providing a gene that helps them adapt to the high altitude, a study suggests.

Past research has concluded that a particular gene helps people live in the thin air of the Tibetan plateau. Now scientists report that the Tibetan version of that gene is found in DNA from Denisovans, a poorly understood human relative more closely related to Neanderthals than modern people.

Denisovans (de-NEE’-soh-vens) are known only from fossils in a Siberian cave that are dated to at least about 50,000 years ago. Some of their DNA has also been found in other modern populations, indicating they interbred with ancient members of today’s human race long ago.

But the version of the high-altitude gene shared by Denisovans and Tibetans is found in virtually no other population today, researchers report in an article released Wednesday by the journal Nature.

That suggests that Denisovans or close relatives of theirs introduced the gene variant into the modern human species, but that it remained rare until some people started moving into the Tibetan plateau, said study main author Rasmus Nielsen of the University of California, Berkeley.

At that point, it conferred a survival advantage and so spread through the Tibetan population, he said in an email. It’s not clear whether the Denisovans were also adapted to high altitudes, he said.

The results show that as early members of today’s human species expanded outside of Africa and encountered new environments, they could call on their genetic legacies from other species, he said. That’s easier than waiting for a helpful genetic mutation to arise, he said.

The Tibetan plateau rises above 13,000 feet (4,000 meters) in elevation. The genetic variant helps survival there by affecting the amount of oxygen the blood can carry when a person is in thin air. Apart from Tibetans, it is found very rarely in Han Chinese and also exists in Mongolians and Sherpas, who are also related to Tibetans and may have picked it up relatively recently, Nielsen said. The researchers found no trace of it outside East Asia.

Todd Disotell, an anthropology professor at New York University who didn’t participate in the study, called the new work “one of the coolest scientific results I have seen in a while…. This is a slam-dunk case.”

David Reich, an expert on ancient DNA at Harvard Medical School, called the paper “important and exciting” in showing the gene came from an ancient human relative. But he said that relative could have been Neanderthals, who are also known to have contributed DNA to modern people.

Nielsen said the Tibetan gene variant doesn’t match any known Neanderthal DNA, but Reich said maybe scientists just haven’t yet found DNA from a Neanderthal who carried it.

___

Online:

Nature: http://www.nature.com/nature

 

The Associated Press

The Associated Press

LEAVE A COMMENT

Discussion | No comments

The Daily Republic does not necessarily condone the comments here, nor does it review every post. Read our full policy

.

Solano News

Christmas comes early to San Marco Street park

By Ryan McCarthy | From Page: A1 | Gallery

 
Travis squadron delivers Christmas gifts to East Tabor

By Ryan McCarthy | From Page: A1 | Gallery

How this chunky Wade met Chunky Wade

By Tony Wade | From Page: A2

 
 
Multiple car accident blocks I-80 in Vacaville

By Glen Faison | From Page: A3, 1 Comment | Gallery

Solano Kwanzaa celebration set for Vallejo return

By Susan Hiland | From Page: A3

 
Lawyers off free legal advice in Fairfield

By Susan Hiland | From Page: A3

 
 
Last-minute shopping at Vacaville Premium Outlets

By Daily Republic staff | From Page: A4 | Gallery

Kitchen fire dislocates family for Christmas

By Susan Hiland | From Page: A4 | Gallery

 
Famous Creations’ toy drive and cupcake sale

By Daily Republic staff | From Page: A4 | Gallery

Fairfield police log: Dec. 20, 2014

By Susan Hiland | From Page: A9

 
Suisun City police log: Dec. 20, 2014

By Susan Hiland | From Page: A9

Weather for Dec. 22, 2014

By Daily Republic | From Page: B10

 
.

US / World

Killer of 2 NYC officers had long criminal history

By The Associated Press | From Page: A1

 
Killings of 2 New York officers trigger backlash

By The Associated Press | From Page: A1

California puzzles over safety of driverless cars

By The Associated Press | From Page: A1

 
Timeline of events before and after NY cop deaths

By The Associated Press | From Page: A1

A look at the 2 NYC officers killed in ambush

By The Associated Press | From Page: A1

 
What’s being said about killings of 2 NYC officers

By The Associated Press | From Page: A1

Exit poll: Ex-regime official is Tunisia’s new president

By The Associated Press | From Page: A5

 
Pakistan makes arrests in Taliban school carnage

By The Associated Press | From Page: A5

Florida authorities say 1 police officer shot and killed

By The Associated Press | From Page: A5

 
Tent city sprouts in shadow of downtown Detroit

By The Associated Press | From Page: A5

US mulls putting NKorea on terrorism sponsor list

By The Associated Press | From Page: A5

 
Satanic Temple puts up display at Michigan Capitol

By The Associated Press | From Page: A5

Australian woman charged with murder of 8 children

By The Associated Press | From Page: A5

 
.

Opinion

Faust and the 2015 federal budget

By Mike Kirchubel | From Page: A8

 
Obama, surgeon general still losing to NRA

By Francis Wilkinson | From Page: A8

Let the music begin

By Colleen Britton | From Page: A8

 
Editorial Cartoon: Dec. 22, 2014

By Daily Republic Syndicated Content | From Page: A8

 
.

Living

Community Calendar: Dec. 22, 2014

By Susan Hiland | From Page: A2

 
Today in History: Dec. 22, 2014

By The Associated Press | From Page: A2

Horoscopes: Dec. 23, 2014

By Holiday Mathis | From Page: B5

 
Horoscopes: Dec. 22, 2014

By Holiday Mathis | From Page: A7

 
.

Entertainment

TVGrid Dec 22

By Daily Republic Syndicated Content | From Page: B6

 
‘Hobbit’ goes out on top with $90.6 million 5-day debut

By The Associated Press | From Page: B7

Good news from Tom Brokaw: His cancer is in remission

By The Associated Press | From Page: B7

 
Review: ‘The Interview’ deserves to be seen

By Jake Coyle | From Page: B7

Happy day: Elton John, David Furnish marry in England

By The Associated Press | From Page: B7

 
TVGrid Dec 23

By Daily Republic Syndicated Content | From Page: B7

.

Sports

Steelers, Packers win, move into playoffs

By The Associated Press | From Page: B1 | Gallery

 
Raiders knock Bills out of playoffs with 26-24 win

By The Associated Press | From Page: B1 | Gallery

Kings snap 5-game losing skid, beat Lakers 108-101

By The Associated Press | From Page: B1 | Gallery

 
Burns gives Sharks late-night win over Blues in OT

By The Associated Press | From Page: B1

The Week Ahead: Not much of a break for Christmas

By Paul Farmer | From Page: B1

 
Super-G crash makes Vonn wait in bid for record

By The Associated Press | From Page: B2

NFL Roundup: Cowboys end 4-year drought, make playoffs

By The Associated Press | From Page: B2 | Gallery

 
7 hurt when lightning strikes near Tampa Bay game

By The Associated Press | From Page: B2

India’s Arjun Atwal wins Dubai Open

By The Associated Press | From Page: B2

 
Documents: FSU QB Winston cleared in conduct hearing

By The Associated Press | From Page: B2

.

Business

Survey: US gas prices fall 25 cents per gallon

By The Associated Press | From Page: B6

 
US companies eager to embrace Cuba face hurdles

By The Associated Press | From Page: B6

.

Obituaries

Marian Kay Zutz

By Nancy Green | From Page: A4

 
Bart Ferro

By Nancy Green | From Page: A4

.

Comics

B.C. Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Wizard of Id Dec 23

By Daily Republic Syndicated Content | From Page: B4

Baby Blues Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Zits Dec 23

By Daily Republic Syndicated Content | From Page: B4

Get Fuzzy Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Pickles Dec 23

By Daily Republic Syndicated Content | From Page: B4

Rose is Rose Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Beetle Bailey Dec 23

By Daily Republic Syndicated Content | From Page: B4

Peanuts Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Garfield Dec 23

By Daily Republic Syndicated Content | From Page: B4

For Better or Worse Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Baldo Dec 23

By Daily Republic Syndicated Content | From Page: B4

Blondie Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Dilbert Dec 23

By Daily Republic Syndicated Content | From Page: B4

Frank and Ernest Dec 23

By Daily Republic Syndicated Content | From Page: B4

 
Sally Forth Dec 23

By Daily Republic Syndicated Content | From Page: B4

Bridge Dec 23

By Daily Republic Syndicated Content | From Page: B5

 
Word Sleuth Dec 23

By Daily Republic Syndicated Content | From Page: B5

Crossword Dec 23

By Daily Republic Syndicated Content | From Page: B5

 
Cryptoquote Dec 23

By Daily Republic Syndicated Content | From Page: B5

Sudoku Dec 23

By Daily Republic Syndicated Content | From Page: B5

 
Rose is Rose Dec 22

By Daily Republic Syndicated Content | From Page: A6

Frank and Ernest Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Blondie Dec 22

By Daily Republic Syndicated Content | From Page: A6

Beetle Bailey Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Garfield Dec 22

By Daily Republic Syndicated Content | From Page: A6

B.C. Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Wizard of Id Dec 22

By Daily Republic Syndicated Content | From Page: A6

For Better or Worse Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Get Fuzzy Dec 22

By Daily Republic Syndicated Content | From Page: A6

Baby Blues Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Baldo Dec 22

By Daily Republic Syndicated Content | From Page: A6

Zits Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Peanuts Dec 22

By Daily Republic Syndicated Content | From Page: A6

Dilbert Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Sally Forth Dec 22

By Daily Republic Syndicated Content | From Page: A6

Pickles Dec 22

By Daily Republic Syndicated Content | From Page: A6

 
Bridge Dec 22

By Daily Republic Syndicated Content | From Page: A7

Word Sleuth Dec 22

By Daily Republic Syndicated Content | From Page: A7

 
Crossword Dec 22

By Daily Republic Syndicated Content | From Page: A7

Sudoku Dec 22

By Daily Republic Syndicated Content | From Page: A7

 
Cryptoquote Dec 22

By Daily Republic Syndicated Content | From Page: A7